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教研室老师近四年获得的基金项目和发表的SCI论文列表

项目名称

课题来源

项目起讫
 
时间

经费
 
(万元)

负责人

蛇床子素衍生物的结构优化与抗MRS活性研究

遵义市科技局

202010-202310

4

杨家强

老鹰茶中吡喃酮并黄烷醇类成分的发现及其抗肿瘤作用机制研究

国家自然科学基金

202101-202412

34

肖世基

遵义地区一株灰树花的菌种分离及栽培驯化研究

遵义市科技局

202010-202310

8

付少彬

基于α-卤代腙的不对称环化反应应用于构建含连续氮原子的杂环化合物的研究

遵义市科学技术局

202010-202310

2

白玫

两种黔产石斛活性成分研究

贵州省科技厅项目

202003-202203

10

肖世基

基于可见光诱导的脱羧碳中心自由基串联环化反应策略的白坚木属生物碱的多样性导向不对称合成研究

国家自然科学基金

202001-202312

40

刘培均

基于TLR4/NF-κB信号通路探寻石上柏双黄酮类抗心肌缺血再灌注损伤成分及其作用机制研究

国家自然科学基金

201901-202212

34

王刚

N-杂卡宾金属配合物MOFs的制备及非均相催化CO2转化研究

国家自然科学基金

201901-202212

40

史大斌

真菌次级代谢产物茯苓酸的结构修饰改造与抗肿瘤活性研究

国家自然科学基金

201901-202212

35

张磊

基于TLR5/NF-κB信号通路探寻石上柏双黄酮类抗心肌缺血再灌注损伤成分及其作用机制研究

遵义市15851人才项目

201901-202112

5

王刚

不饱和重氮酮缩环重排:机理研究与合成应用

国家自然科学基金

201801-201212

38

赵亮

蛇床子素的结构修饰与抗MRSA活性研究

贵州省中医药管理局

201808-201912

2.5

杨家强

不饱和重氮酮缩环重排:机理研究和合成应用

贵州省教育厅

201711-202010

6

赵亮

鬼臼毒素类MDR逆转剂的合成及其经ROS/MAPK通路抗白血病细胞耐药的机制研究

贵州省教育厅

201710-202009

10

张磊

单加氧酶及其辅酶因子共表达工程菌的构建及其在不对称氧化反应中的应用

贵州省教育厅

201711-202011

6

白玫

 

 

 

 

 

 

年、卷、期号
 
起止页码

第一作者

通讯作者

Selective   alkylation of beta-anhydroicaritine and their biological evaluation on   anticancer

Natural Product   Research

2020,11

 

赵长阔

Synthesis and   biological evaluation of camptothecin substituted norcantharimide derivatives

Natural Product   Research

2020,10

赵长阔

Base promoted   regioselective aromatization for the preparation of substituted   3-hydroxybenzene dicarboxylate

Joural of   Heterocyclic Compounds

2020,57(8):3167-3172

赵长阔

Cascade   substitution reaction between oxabornene and amines to construct   cyclohexa-1,4-diene-3,6-diamine and amino alcohol

Joural of   Heterocyclic Compounds

2020,57(4):1893-1900

赵长阔

赵长阔

Visible-Light-Induced   Radical Defluoroborylation of Trifluoromethyl Alkenes: An Access to   gem-Difluoroallylboranes

Advanced Synthesis   & Catalysis

2020, 362(14),   2990–2996

刘培均

Transition-metal-free   radical relay cyclization of vinyl azides with 1,4-dihydropyridines involving   a 1,5-hydrogen-atom transfer: access to α-tetralone scaffolds

Organic Chemistry   Frontiers

2020, 7(22),   3638–3647

刘培均

Ionic   Liquid–Microwave–Based Extraction of Amentoflavone from Selaginella   trachyphylla

Bangladesh J. Bot

2020,48(3): 861-868

王刚

Analysis of the   Volatile Components in Selaginella
  doederleinii by Headspace Solid Phase
  Microextraction-Gas
  Chromatography-Mass Spectrometry

Molecules

2020, 25: 115-129.

王刚

含膦酸酯的L_苯丙氨酸二肽衍生物的合成及其抗肿瘤作用

精细化工

2020, 37(6): 1249-1252+1281

杨家强

杨家强

Two new bibenzyl   compounds from Dendrobium lindleyi

Records of Natural   Products

2020, 14(6):416-420

肖世基

A new dopamine   derivative from Cotidius chinensis

Records of Natural   Products

2020, 14(5):361-365

肖世基

Dihydrophenanthrofurans   and bisbibenzyl derivatives from the stems of Dendrobium nobile

Fitoterapia

2020,142:104586.

肖世基

Dendrobine-type   alkaloids and bibenzyl derivatives from Dendrobium findlayanum

Fitoterapia

2020, 142:104497

肖世基

Lignans from the   heartwood of Nothotsuga longibracteata

Chinese Journal of   Organic Chemistry

2020,   40(12):2120-2126

肖世基

Investigation of   Chemical Compounds and DPPH Radical Scavenging Activity of Oudemansiella   raphanipes (Agaricomycets) Based on Fermentation

International Journal of Medicinal Mushrooms

2020, 22(3):   299-304.

付少彬

Morelsins A–F, six   sesquiterpenoids from the liquid culture of Morchella importuna

Tetrahedron

2020,76(31-32):131356

付少彬

Preparation of   Uracil by bacteria isolated from Morchella

Pakistan Journal of Pharmaceutical Sciences.

 2020332):621-625

付少彬

A new alkanol from   the endolichenic fungus Daldinia.

J. Chin. Chem. Soc.

online

付少彬

Catalyst-Free and   Visible Light Promoted Aminofluoroalkylation of Unactivated Alkenes: An   Access to Fluorinated Aziridines

Adv. Synth. Catal.

2020, 362:   2604-2608.

赵亮

Difluoroalkylation   of alkenes promoted by noncovalent interaction: A general method for the   synthesis of difluoro-contained dihydrobenzofurans and indolins

Tetrahedron Letters

2020, 61, 152558.

赵亮

Cobalt-catalyzed C2α-acyloxylation of 2-substituted indoles with   tert-butyl peresters

Org. Biomol. Chem.

2019,17(13), 3343-3347.

 

刘培均

Silver-promoted decarboxylative radical addition/annulation of   oxamic acids with gem-difluoroolefins: concise access to CF2-containing   3,4-dihydroquinolin-2-ones

Org. Biomol. Chem.

2019, 17(37), 8527-8532.

 

刘培均,

Radical Hydroboration and Hydrosilylation of   gem-Difluoroalkenes: Synthesis of α-Difluorinated Alkylborons and   Alkylsilanes

Org. Lett.

2019, 21(20), 8454-8458.

 

刘培均

金钗石斛中联苄基衍生物化学成分研究

有机化学

online

张茂生

肖世基

Chemical constituents of Bletilla striata

Journal of Asian   Natural Products Research

online

 

肖世基

Chemical Constituents from the Aerial Parts of Daucus carota

Chemistry of   Natural Compounds

2019,55(4):665-668

 

肖世基

Two new lignans from Gymnotheca involucrata

Natural Product   Research

 

肖世基

肖世基

Crystal structure of dimethyl 5-(10-(methoxycarbonyl)anthracen-9-yl)isophthalate,C26H20O6

Z. Kristallogr. NCS

2019, 234(1): 115–117

 

史大斌

Visible light   promoted fluoroalkylation of alkenes and alkynes using 2-bromophenol as a   catalyst

Chemical   Communications

2019, 55(81):   12259-12262.

 

赵亮

Two New Echinocystic Acid Derivatives Catalyzed by Filamentous   Fungus Gliocladium roseum CGMCC 3.3657

Natural Product   Research

2019,33(13):1842-1848.

 

付少彬

New Phomalone derivatives from endolichenic fungus Cochliobolus   kusanoi  in Ny-Alesund, Arctic

J. Chin. Chem. Soc.

2019;66:325–329

 

付少彬

Secondary Metabolites and Antiradical Activity of Liquid   Fermentation of Morchella sp. Isolated from Southwest China

Molecules

2019, 24(9), 1706-1714

 

付少彬

Separation and chemical constituents of Morchella conica   isolated from Guizhou Province China

Biochemical   Systematics and Ecology

accepted

 

付少彬

Thiourea-catalyzed asymmetric domino Michael-cyclization   reaction of 3-isothiocyanato oxindoles with β,γ-unsaturated   α-keto esters for the synthesis of   spirocyclic oxindoles.

Tetrahedron

2019, 75(14): 2155~2161.

白玫

 

SEPARATION OF HINOKIFLAVONE FROM SELAGINELLA DOEDERLEINII HIERON   BY IONIC LIQUID-MODIFIED SILICA GEL

Bangladesh J. Bot

2019,48(3): 861-868.

 

王刚

CHEMICAL COMPOSITION AND ANTIOXIDANT EFFECT OF ESSENTIALOILS OF   THREE MEDICINAL SPECIES OF SELAGINELLA P. BEAUV.

Bangladesh J. Bot

2019,48(3): 853-860.

 

王刚

Preparation of   Dolutegravir Intermediate Diastereomer

J. Heterocyclic   Chem.

2019, 56 (5):   2063-6067

 

赵长阔

Synthesis and   Biological Activity Evaluation of CampthothecinHAANorcantharidin   Conjugates as Antitumor Agents in Vitro

Chemical Biology   & Drug Design.

2019, 93: 986-992

 

赵长阔

Synthesis of   Campthothecin-Glycine-Norcantharidin Conjugates and Their Biological Activity   Evaluation In Vitro

Latin American Journal   of Pharmacy.

2019, 38 (5):   954-960

 

赵长阔

Synthesis of Dual   Target CPT-Ala-Nor Conjugates and Their Biological Activity Evaluation

Anti-Cancer Agents   in Medicinal Chemistry

2019, 19(4):   502-508

赵长阔

赵长阔

Synthesis of   Norcantharidin Complex Salts

J. Heterocyclic   Chem.

2019, 56 (5):   1567-1670

赵长阔

赵长阔

含膦酸酯结构单元的磺胺衍生物合成与抗菌活性

精细化工

2019 , 36 (9)1869-1873

杨家强

杨家强

Iodine-catalyzed   oxidative annulation of 3-cyanoacetylindoles with benzylamines: facile access   to 5-(3-indolyl)oxazoles

Organic & biomolecular   chemistry

2018,   16(19): 3572-3575

 

刘培均

Iodine-Catalyzed   C–H Amidation and Imination at the 2α-Position of 2,3-Disubstituted Indoles   with Chloramine Salts

Journal of organic chemistry

2018,   83(8): 4665-4673

 

刘培均

Biocatalysis   of ursolic acid by the fungus Gliocladium roseum CGMCC 3.3657 and resulting   anti-HCV activity

RSC Advances

2018,   8(29): 16400-16405

付少彬

付少彬

Design,   synthesis and antineoplastic activity of novel hybrids of podophyllotoxin and   indirubin against human leukaemia cancer cells as multifunctional anti-MDR   agents

Bioorganic & medicinal   chemistry letters

2018,   28(10): 1817-1824

 

张磊

A   simple route to a novel acid-sensitive 20(S)-O-linked camptothecin   norcantharidin acid ester derivative

Royal Society Open Science

2018,   5(2): 170842

赵长阔

 

The   Regio-selective Synthesis of 10-Hydroxy Campthothecin Norcantharidine   Conjugates and Their Biological Activity Evaluation in Vitro

Royal Society Open Science

2018,   5(6): 172317

赵长阔

 

Mahimbrine   A, a Novel Isoquinoline Alkaloid Bearing a Benzotropolone Moiety from Mahonia   imbricata

Molecules

2018,   23(7): 1539

张茂生

肖世基

Chloramine   Salt Mediated Oxidative Halogenation of Terminal Alkynes with KI or NaBr:   Practical Synthesis of 1-Bromoalkynes and 1-Iodoalkynes

Synlett

2018;   29(15): 2051-2055

 

刘培均

Design,   synthesis and biological evaluation of novel nitric oxide-donating   podophyllotoxin derivatives as potential antiproliferative agents against   multi-drug resistant leukemia cells

RSC Advances

2018,   8(60): 34266-34274

张磊

 

Palladium/copper-catalyzed   tandem Sonogashira coupling/lactonization
  of methyl 2-(20,20-dibromovinyl)benzoate with terminal alkynes: Facile
  access to 3-alkynyl isocoumarins

Tetrahedron Letters

2018,   59(32): 3151-3154

 

刘培均

Design,   Synthesis and Biological Activity Evaluation of CampthothecinHAANorcantharidin   Conjugates as Antitumor Agents in Vitro

Chemical biology & drug   design

 

 

赵长阔

Ionic   Liquid–Ultrasound-Based Extraction of Biflavonoids from Selaginella helvetica   and Investigation of Their Antioxidant Activity

Molecules

2018,   23(12), 3284

 

王刚

Chemical   constituents from Tsuga longibracteata and its chemotaxonomic study

Biochemical Systematics and   Ecology

2018,   77: 4-6

 

肖世基

Two   New Sesquterpenoids from Fructus Carotae

Chinese Journal of Organic   Chemistry

2018,   38(7): 1829-1832

 

肖世基

Synthesis   of 4Methylimidazole2Carboxylic   Acid

Journal of Heterocyclic   Chemistry

2018,   55(11): 2619-2622

 

赵长阔

New   phomalone derivatives from the endolichenic fungus Cochliobolus kusanoi in NyAlesund   Arctic

Journal of the Chinese Chemical   Society

accept

付少彬

付少彬

Synthesis,   antitumor evaluation and molecular docking study of a novel   podophyllotoxin-lonidamine hybrid

Medicinal Chemistry Research

2018,   27(10): 2231-2238

张磊

 

Microbe-mediate   transformation of echinocystic acid by whole cells of filamentous fungus   Cunninghamella blakesleana CGMCC 3.910

Molecular Biology Reports

2018,   45(6): 2795-2800

付少彬

付少彬

Sealed   tube promoted coupling of camptothecin and norcantharidin acid ester and   their preliminary biological activity evaluation in vitro

Medicinal Chemistry Research

2018,   27(2): 406-411

 

赵长阔

Continuous   Flow Processing:In situ Preparation of Imatinib Freebase

Latin American Journal of   Pharmacy

2018,   37(6): 1251-1256

 

赵长阔

Ring   Open to Mono Ester of Norcantharidin Derivatives Also Can Inhibit Hep G2 Cell   Line?

Latin American Journal of   Pharmacy

2018,   37(3): 470-474

赵长阔

 

3D-QSAR   Studies of the Pteridine Analogues as iNOS Inhibitors

Chinese Journal of Structural   Chemistry

2018,   37(9): 1371-1378

张磊

 

MIL-101负载Pd纳米颗粒高效非均相催化苯并呋喃选择性C2位芳基化

有机化学

2018,   38, 832-839

 

史大斌

Two   new echinocystic acid derivatives catalyzed by filamentous fungus Gliocladium   roseum CGMCC 3.3657

Natural Product Research

2018:   1-7

付少彬

付少彬

Crystal   structure of methyl 10-(pyridin-4-yl)-anthracene-9-carboxylate, C21H15NO2

Zeitschrift für   Kristallographie - New Crystal Structures

2018,   233(3): 441-443

 

史大斌

Crystal   structure of methyl 4′-amino-3′,5′-dimethyl-[1,1′-biphenyl]-4-carboxylate,   C16H17NO2

Zeitschrift für   Kristallographie - New Crystal Structures

2018,   233(3): 431-433

 

史大斌

Crystal   structure of methyl 4′-amino-3′,5′-diisopropyl-[1,1′-biphenyl]-4-carboxylate,   C20H25NO2

Zeitschrift für   Kristallographie - New Crystal Structures

2018,   233(3): 421-422

 

史大斌

Design,   synthesis and biological evaluation of indole carboxylic acid esters of   podophyllotoxin as antiproliferative agents

Medicinal Chemistry Research

接收

张磊

 

Chemical   Constituents from the Aerial Parts of Daucus carota

Chemistry of Natural Compounds

已接收

 

肖世基

Chemical   Composition of Essential Volatile Oils ofSelaginella SPP. and their   Antibacterial Activity

Bangladesh Journal of Botany

2018,47(3):   719-726.

王刚

 

Profiling   of the Volatile Conponents in Selaginella
  Based on HS-SPME and GC-MS

Bangladesh Journal of Botany

2018,47(3):   719-726.

 

王刚

含氟3-羟基吲哚-2-酮衍生物的合成及抗癌活性

精细化工

2018,   35(6): 1022-1028

王京

张磊

膦酸酯糖苷衍生物的合成与抗肿瘤活性

精细化工

 

杨家强

杨家强

 

2017年获国家级、省级大学生创新创业训练计划项目

指导教师

学生

项目名称

项目类型

项目编号

项目级别

王刚

袁仕梦

固定化离子液体富集分离石上柏中穗花杉双黄酮的应用研究

创新训练项目

 

201710661012

省级、国家级

付少彬

常雪雪

遵义地区野生羊肚菌菌种分离及驯化 

 

创新训练项目

 

201710661037

省级、国家级

2017年获校级大学生创新创业训练计划项目

指导教师

学生

项目名称

项目类型

徐应淑

郭福照

地榆皂苷自微乳的制备工艺研究

创新训练重点项目

肖世基

杨进

杓唇石斛化学成分分离与分析

 

创新训练重点项目

徐应淑

罗珊

茶多酚脂质体凝胶剂的制备工艺研究

创新训练一般项目

肖世基

孙福忍

 

凤眼莲化学成分提取分离及鉴定

 

创新训练一般项目

付少彬

王梦娇

羊肚菌液体发酵技术及化学成分初探

创新训练一般项目

 

 

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