1. 中药活性成分及药理作用机制研究，重点围绕黄酮类等天然产物在抗炎、抗肿瘤、保肝等方面的作用及相关信号通路。

2. 传统药用植物的物质基础与质量评价研究，通过成分分离鉴定、指纹图谱和质量标志物筛选，为中药制剂标准化和工业化生产提供理论与技术支撑。

3. 生药资源开发与综合利用研究，围绕黔药及其加工副产物的高值化利用，开展有效部位开发、功能制剂/健康产品研制与工艺优化。

[1] Fang Y, Wu Y, Meng Y, Qiu X, Huang L, Zhang M, Guo D, Liang G, Yang J, Dong M, Sun C, and Xiao S. (2026) Dimeric Furanones with a Unique Polycyclic Spiro Skeleton from Hawk Tea[J]. Journal of Organic Chemistry. 91(8): 3109-3117.

https://doi.org/10.1021/acs.joc.5c02725

[2] Guo D, Cong J, Zhang M, Dong M, Liang G, Sun C, Wu W, and Xiao S. (2025) A Rare Sesquiterpene from Hawk Tea[J]. Chinese Journal of Organic Chemistry. 45(9): 3486-3489.

https://doi.org/10.6023/cjoc202502012

[3] Ren M, Sun G, Ding X, Yu X, He L, Xiao S, Dong M, Yang J, Ding K, and Sun C. (2025) A polysaccharide from Gynostemma pentaphyllum: structure characterization and anti-insulin resistance potential through Galectin-3 modulation[J]. International Journal of Biological Macromolecules. 310(Pt 4): 143618.

https://doi.org/10.1016/j.ijbiomac.2025.143618

[4] Meng Y, Yuan J, Zhang M, Guo D, Cao P, Yang J, Dong M, Dai J, Sun C, and Xiao S. (2025) Diterpenoids from the bark of Torreya grandis and their cytotoxicity activity[J]. Fitoterapia. 181: 106376.

https://doi.org/10.1016/j.fitote.2025.106376

[5] Wu Y, Dong M, Sun C, Zhang M, and Xiao S. (2025) A new biflavanol from bark of Nothotsuga longibracteata[J]. Journal of Asian Natural Products Research. 27(7): 1080-1086.

https://doi.org/10.1080/10286020.2024.2446282

[6] Yuan J, Meng Y, Zhang M, Guo D, Yang J, Dong M, Sun C, and Xiao S. (2024) Isoprenoid flavonoids isolated from Sophora davidii and their activities induces apoptosis and autophagy in HT29 cells[J]. Fitoterapia. 175: 105945.

https://doi.org/10.1016/j.fitote.2024.105945

[7] Yang Z, Luo W, Yang Z, Zhang M, Dong M, Guo D, Gu J, Sun C, and Xiao S. (2024) Diterpenoids from Torreya grandis and their cytotoxic activities[J]. Phytochemistry. 221: 114036.

https://doi.org/10.1016/j.phytochem.2024.114036

[8] Zhang M, Jiang Y, Cheng L, Yang J, Dong M, Sun C, and Xiao S. (2023) Structural elucidation of lactone derivatives from Dendrobium pendulum[J]. Magnetic Resonance in Chemistry. 61(8): 481-486.

https://doi.org/10.1002/mrc.5370

[9] Meng Y, Zhang M, Fang Y, Yang J, Dong M, Sun C, and Xiao S. (2023) Secondary Metabolites from Dendrobium nobile and Their Activities Induce Metabolites Apoptosis in OSC-19 Cells[J]. Molecules. 28(8): 3423.

https://doi.org/10.3390/molecules28083423

[10] Huang L, Meng Y, Wang G, Yang J, Zhang M, Dong M, Sun C, and Xiao S. (2023) Complete ¹H and ¹³C assignments of two new sesquiterpenoids from Dendrobium aduncum[J]. Magnetic Resonance in Chemistry. 61(6): 386-391.

https://doi.org/10.1002/mrc.5345

[11] Cheng L, Fang Y, Zhang M, Wang G, Dong M, Sun C, and Xiao S. (2023) Dihydrophenanthrenes and phenanthrenes from Dendrobium terminale[J]. Natural Product Research. 37(14): 2375-2382.

https://doi.org/10.1080/14786419.2022.2048379

[12] Dong M, Yi Q, Shen D, Yan J, Jiang H, Xie J, Zhao L, and Gao H. (2022) A combined metabolomics and molecular biology approach to reveal hepatic injury and underlying mechanisms after chronic L-lactate exposure in mice[J]. Computational and Structural Biotechnology Journal. 20: 3935-3945.

https://doi.org/10.1016/j.csbj.2022.07.034

[13] Yang Z, Zhang Y, Yang J, Luo W, Zhang M, Wang G, Sun C, Dong M, and Xiao S. (2022) Chemical constituents from Dendrobium moschatum (杓唇石斛化学成分研究)[J]. Chinese Traditional Patent Medicine. 44(11): 3517-3521.

[14] Luo W, Wang M, Yang Z, Zhang M, Wang G, Sun C, Dong M, and Xiao S. (2022) Chemical constituents from Dendrobidium strongylanthum (梳唇石斛化学成分的研究 )[J]. Chinese Traditional Patent Medicine. 44(10): 3192-3195.

[15] Cheng L, Fang Y, He H, Zhang M, Dong M, Sun C, and Xiao S. (2022) Two New Bibenzyls from Dendrobium hercoglossum[J]. Records of Natural Products. 16(4): 353-357.

https://doi.org/10.25135/rnp.291.2109.2198