1.天然产物调控细胞程序性死亡抗病毒、抗肿瘤作用和机制研究

2.基于炎症/癌症微环境响应的药物递送系统研究

1.遵义市校联合基金，地榆皂苷I调控溶酶体自噬阻抑白血病干细胞向AML发生发展的作用机制研究，2024-2026，30万，主持

2.国家自然科学基金，基于GCN5乙酰化修饰调控TFEB-自噬溶酶体通路探讨辣木籽活性成分MoringaA广谱抗流感病毒的作用及机制，2023-2026，34万，主持

3.贵州省科技厅支撑计划，基于TNF-β通路的辣木籽活性成分MoringaA抗甲型H1N1的作用机制研究与示范，2021-2024，32万，主持

4.贵州省科技厅基础研究计划，骨髓抑制激发的造血干细胞自噬对白细胞影响的分子机制及地榆皂苷的调控作用研究，2018-2021，30万，主持

5.国家自然科学基金，基于Sirt3/Nrf2抗氧化途径研究淫羊藿次苷Ⅱ预处理对脑缺血-再灌注损伤的保护作用，2018-2021，34万元，参与

1.Leichen,Meijun Liu, Yongai Xiong*,et al.Interactions between Traditional Chinese Medicine and Gut Microbiota in Chronic Diseases[J].Pharmacological Research-Modern Chinese Medicine.2025

2.Wenhui Wu,Ruidong Li,Yongai Xiong*,et al.Targeting ZBP1-mediated PANoptosis: inflammation responsive selenized chitosan nanoparticles loaded with Moringa A for anti-viral pneumonia therapy[J].Biomaterials research.2025.(IF=9.6)

3.Lei Chen,Chunmei Lv,Yongai Xiong*,et al.Anti-viral pneumonia and gut microbiota regulatory effects of a polysaccharide purified from Moringa Oleifera Seeds[J].NPJ Science of food.2025.(IF=7.8)

4.Tingting Chen,Dandan Yang,Yongai Xiong*,et al.Mechanism and spectrum effect relationship of Shen-Ling-Bai-Zhu-San in treating viral pneumonia via inhibiting the PI3K/AKT/NF-κB signaling pathway[J].Journal of Ethnopharmacology.2025.(IF=5.4)

5.Xu Cheng, Taoyuan Zeng,Yongai Xiong*,etal.The emerging role of PANoptosis in viral infections disease[J].Cellular Signalling.2025.(IF=4.4)

6.Shunqiang Song, Liangyu Yang,Yongai Xiong*, et al.Enteric Delayed-Release Granules Loading Dendrobine Ameliorates Hyperlipidemia in Mice by Regulating Intestinal Flora Composition[J].Pharmaceutics.2024.(IF=5.5)

7.Chunmei lv, Ruidong Li,Yongai Xiong*, et al.Broad-spectrum antiviral effect of MoringaA‐loaded exosomes against IAV by mediating the GCN5‐TFEB‐autolysosome pathway[J].Journal Of Medical Virology.2024.(IF=6.9)

8.Yongai Xiong.The emerging role of PANoptosis in cancer treatment[J].Biomedicine&Pharmacotherapy.2023.(IF=7.5)

9.HongWang, Lei Chen,Yongai Xiong*,et al.Polydopamine-coated mesoporous silica nanoparticles co-loaded with Ziyuglycoside I and Oseltamivir for synergistic treatment of viral pneumonia[J].International Journal of Pharmaceutics.2023.(IF=5.8)

10.Yongai Xiong*,Tingting Chen, Lei Chen,et al.Gold Nanoparticles Coated with SH-PEG-NH2 and Loaded with Ziyuglycoside I for Promoting Autophagy in Hematopoietic Stem Cells[J].International Journal of Nanomedicine.2023.(IF=8.0）

11.Lei Chen,Tingting Chen,Yongai Xiong*,etal.Recent advances in the study of the immune escape mechanism of SFTSV and its therapeutic agents[J].Viruses.2023.(IF=5.8)

12.Xiao Guo, Xinghong Gao,Yongai Xiong*,etal.Clinical advances in non-replication structure mRNA vaccines of viral diseases[J].VirologyJournal.2023.(IF=5.9)

13.Liangyu Yang, Lei Chen,Yongai Xiong*,et al.The crosstalk between classic cell signaling pathways, non-coding RNAs and ferroptosis in drug resistance of tumors[J].Cellular Signalling.2023.(IF=4.8)

14.Yue Liu,Liangyu Yang,Yongai Xiong*,et al.RecentAdvances in Antiviral Activities of Triterpenoids[J].Pharmaceuticals.2022.(IF=4.8)

15.Yongai Xiong,Riaz Rajoka MS,He Zhendan, etal. Isolation and identification of two new compounds from the seeds ofMoringa oleiferaand their antiviral and anti-inflammatory activities[J].Nat Prod Res.2022.(IF=2.2)

16.Yongai Xiong,Yandong Tang, Chunfu Zheng. Thecrosstalk betweencaspases family and cGAS-STING signaling pathway[J].Journal of Molecular Cell Biology (JMCB).2021.(IF=8.2)

17.Tingting Song, Hong Wang,Yongai Xiong*.et al.TPGS-modified Long-circulating Liposomes Loading Ziyuglycoside I for Enhanced Therapy of Myelosuppression[J].International Journal of Nanomedicine.2021.(IF=8.0）

18.Mehwish H.M., Shahid Riaz R.Muh,Yongai Xiong, et al. Therapeutic potential of Moringa seed polysaccharide embedded silver nanoparticles in wound healing [J].International Journal of Biological Macromolecules.2021.(IF=8.0）

19.Yongai Xiong, Shahid Riaz M, Zhendan H, et al.Virucidal activity ofMoringaA fromMoringa oleiferaseeds against Influenza A Viruses by regulating TFEB[J].Int Immunopharmacology.2021.(IF=5.7)

20.Shahid Riaz R.Muh,Mehwish H.M.,Yongai Xiong,et al.Gut microbiota targeted , nanomedicine for cancer therapy: Challenges and future considerations[J].Trends in Food Science & Technolog.2020. (IF=16.0)

21.Yongai Xiong,Ya Z, Wang S, et al. Development and In Vivo Evaluation of Ziyuglycoside I-Loaded Self-Microemulsifying Formulation for Activity of Increasing Leukocyte[J].AAPS PharmSciTech.2019.(IF=4.0)