师资队伍

肖世基
职称:教授
领域:药物化学
联系电话:0851-28642513
电子邮箱:xiaoshji84@163.com
办公室(实验室):药物化学教研室

肖世基,男,博士,教授,博士生导师,苗族,毕业于四川大学/中科院成都生物研究所,药物化学教研室副主任(主持工作),贵州省菌物学会理事,贵州省药学会药物化学专业委员会委员。主要从事天然药物中小分子化学成分的提取分离、结构鉴定及其生物活性研究。主持国家自然科学基金2项、省部级课题等6项。在国内外期刊发表论文100余篇,其中SCI第一作者或者通讯作者论文50余篇,授权国家发明专利10项;贵州省药学科技二等奖(排名第一),贵州省医学科技一等奖(排名第五),贵州省医学科技三等奖(排名第四)。承担本科生《天然药物化学》、《有机化学》,研究生《波谱解析》教学工作,招收微生物与生化药学专业和生药学专业硕士生。


植物/中药/大型真菌/茶产品中化学成分的分离纯化,结构鉴定及其生物活性研究。招收微生物与生化药学专业和生药学专业硕士生。



  1. 1.何芋岐、鲁艳柳、白朝钧、肖世基、张建永、杨继勇、陈集双、杨洲. 贵州道地药材金钗石斛优势物质基础及品质挖掘推动乡村振兴产业示范,2022年,贵州省医学科技奖一等奖。

  2. 2.肖世基、张茂生、孙成新。几种西南特色药用植物化学成分,2023, 贵州省药学会科技奖二等奖。

  3. 3.徐德林、李林、闻伟锷、肖世基、钱刚. 药用兰科植物白及资源开发的关键技术研究,2024年,贵州省医学科技奖三等奖。

1. Jingjing Yuan#, Junru Guo#, Dongyang Guo, Dale Guo, Minjian Dong, Chengxin Sun, Maosheng Zhang*, Shiji Xiao*. Gloeosterincarines A–H, eight new sesquiterpenes from Gloeostereum incarnatum [J]. Journal of Molecular Structure, 2025, 1335:141969. (中科院二区)

2. Yu-Fan Meng#, Jing-Jing Yuan#, Mao-Sheng Zhang, Da-Le Guo, Min-Jian Dong, Jun Dai*, Cheng-Xin Sun*, Shi-Ji Xiao*. Diterpenoids from the bark of Torreya grandis and their cytotoxicity activity [J]. Fitoterapia, 2025, 181: 106376. (中科院三区)

3. Jingjing Yuan#, Yufan Meng#, Maosheng Zhang, Dale Guo, Jianwen Yang, Minjian Dong, Chengxin Sun*, Shiji Xiao*. Isoprenoid Flavonoids Isolated from Sophora davidii and Their Activities Induces Apoptosis and Autophagy in HT29 cells [J]. Fitoterapia, 2024, 175:105945. (中科院三区)

4. Zong-Yu Yang#, Wan-Li Luo#, Zai-Wen Yang, Mao-Sheng Zhang, Min-Jian Dong, Cheng-Xin Sun*, Shi-Ji Xiao*. Diterpenoids from Torreya grandis and their cytotoxic activities [J]. Phytochemistry, 2024, 221: 114036.(中科院二区)

5. Lei Cheng, Yi-Ke Fang, Mao-Sheng Zhang, Gang Wang, Min-Jian Dong, Cheng-Xin Sun*, Shi-Ji Xiao*. Dihydrophenanthrenes and phenanthrenes from Dendrobium terminale[J]. Natural Product Research, 2023, 37(14): 2375-2382. (中科院三区)

6. Mao-Sheng Zhang, Yu Jiang, Lei Cheng, Jian-Wen Yang, Min-Jian Dong, Cheng-Xin Sun, Shi-Ji Xiao*. Structural elucidation of lactone derivatives from Dendrobium pendulum lactone derivatives from Dendrobium pendulum [J]. Magnetic Resonance in Chemistry, 2023, 61(8):481-486. (中科院三区)

7. Yu-Fan Meng, Mao-Sheng Zhang, Jian-wen Yang, Min-Jian Dong, Cheng-Xin Sun *, Shi-Ji Xiao*. Secondary metabolites from Dendrobium nobile and their activities induces metabolites apoptosis in OSC-19 cells. Molecules, 2023, 28(8):3423. (中科院二区)

8. Ting Mao,  Xiao-Xiao Liu, Weipiao Li, Gai-Rong Wang, Wen-Yong Han, Jie Tong, Shi-Ji Xiao*, Liang Zhao*, Chun-Yang He*. Synthesis of Fluoroalkylated Pyrrolidines through Neat Reaction of Fluoroalkyl Iodides with N, N-diallylarylamines[J]. Advanced Synthesis & Catalysis, 2023, 365:1-7. (中科院二区)

9.Lang Huang, Yu-Fan Meng, Gang Wang , Jian-wen Yang, Mao-Sheng Zhang, Min-Jian Dong , Cheng-Xin Sun*, Shi-Ji Xiao*. Complete 1H and 13C assignments of Two new sesquiterpenoids from Dendrobium aduncum[J]. Magnetic Resonance in Chemistry, 2023, 61(6):386-391. (中科院三区)

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