Zhongqiang Wang is a graduate of Northwest A & F University (B.S.) and the Australian National University where he completed his Ph.D. under the supervision of Professor Chris J. Easton.

Zhongqiang then moved back to China to work with Professor Yongzheng Chen at the Zunyi Medical University, on areas of development of novel protein engineering techniques for bacterial cytochrome P450 monooxygenases for applications in organic synthesis, using nonproteinogenic amino acids.

Office 2-102

School of Pharmacy, Zunyi Medical University

Zunyi, Guizhou Province 563000

Updated: 23th Nov 2023

PROFESSIONAL

2016.03 - 2018.01  Assistant Experimentalist, Reseach School of Chemistry, The Australian National University

2018.02 - present Lecturer, School of Pharmacy, Zunyi Medical University

TEACHING

负责课程：《制药分离工程》、《生物制药概论》（English）

承担课程：《制药工艺学》、《药物合成方法与技术》

（1）王中强，袁利.应用型本科院校制药工艺学课程改革实践[J]. 名族文汇-教学与实践，2022（8）：285

（2）Zhongqiang Wang, Li Yuan. Innovation of the Development Path of Higher Education Based on the Concept of “Integration of Science and Education and Interdependence of Speculation”. Advances in Educational Technology and Psychology, 2022 5th International Conferences on Advances in General Education and Education Development, 53-57.

EDUCATION

The Australian National University, Canberra, Australia     Ph.D.  2017 Synthetic biology

Northwest A & F University, Shanxi, China               B.S.  2010 Food Science and Technology

RECENT HORNORS & AWARDS

2020    获得第五届全国高校青年教师教学竞赛贵州省省级选拔赛二等奖

2020    获得"2020年度遵义医科大学优秀教师"荣誉称号

2022    遵义医科大学药学院首届思政主题教案比赛二等奖

FUNDING

2020    National Natural Science Foundation of China, (Engineering the P450DA Monooxygenase with               Fluorinated Amino Acids for Chiral β-Halohydrin Synthesis)

2021    贵州省科技计划项目, 基于氟取代氨基酸修饰 P450DA 单加氧酶绿色合成重要医药中间体 β-卤代醇的研究

PREOFESSIONAL ACTIVITIES

Academic

2022         中国生物工程学会科普工作委员会委员

2022         贵州省药学会药物化学专业委员会委员

2011-present    澳大利亚皇家化学学会会员

Social

2022         遵义医科大学归国华侨侨眷联合会副秘书长

2012         澳大利亚首都地区中国学联，澳大利亚国立大学中国学生学者联谊会组织发起人

PUBLICATIONS

（1）Zhongqiang Wang; Ling Zhao; Xueqing Mou; YongzhengChen*. Enzymatic approaches to site-selective oxidation of quinoline and derivatives. Organic & Biomolecular Chemistry, 2022, 20 (13), 2580-2600.

（2）Ke Chen; Zhongqiang Wang*; Kan Ding*; Yongzheng Chen*; Yasuhisa Asano*; Recent progress on discovery and research of aldoxime dehydratases, Green Synthesis and Catalysis, 2021, 2(2), 179–186

（3）Zhongqiang Wang*; Hayden Matthews*; Guozhong Deng; Xiaojian Zhou; and Yongzheng Chen; Thermodynamic analysis of tyrosyl-tRNA synthetases revealed bacterial-selective tyrosine derivatives, Australian Journal of Chemistry, 2021, 74(10), 740–745.

（4）Wang Zhongqiang*; Matthews Hayden*; Translational incorporation of modified phenylalanines and tyrosines during cell-free protein synthesis, RSC Advances, 2020, 10(19): 11013-11023.

（5）Kailin Wu#, Linchao Tang, Haibo Cui, Nanwei Wan*, Ziyan Liu, Zhongqiang Wang, Shimin Zhang, Baodong Cui, Wenyong Han, Yongzheng Chen*, Biocatalytical Asymmetric Sulfoxidation by Identifying Cytochrome P450 from Parvibaculum Lavamentivorans DS‐1, ChemCatChem, 2018, 10(23): 5410-5413.

（6）Huihui Wang#, Nanwei Wan*, Lin Ma, Zhongqiang Wang, Baodong Cui, Wenyong Han, Yongzheng Chen*, A novel and simple spectrophotometric method for detection of nitrite in water, Analyst, 2018, 143(19): 4555-4558.

（7）Maoyao Wang, Xiaojian Zhou, Zhongqiang Wang; Yongzheng*; Enzyme-catalyzed allylic oxidation reactions: A mini-review. Front Chem. 2022; 10: 950149.

（8）Tao Peng; Jin Tian; Yuyan Zhao; Xu Jiang; Xiaoling Cheng; Guozhong Deng; Quan Zhang; Zhongqiang Wang; Jiawei Yang; Yongzheng Chen; Multienzyme Redox System with Cofactor Regeneration for Cyclic Deracemization of Sulfoxides. Angewandte Chemie International Edition, 2022, 61 (37), e202209272. doi: 10.1002/anie.202209272.

（9）Nanwei Wan; Haibo Cui; Ling Zhao; Jing Shan; Ke Chen; Zhongqiang Wang; Xiaojian Zhou; Bao‐Dong Cui; Wenyong Han; Yongzheng Chen; Directed evolution of cytochrome P450DA hydroxylase activity for stereoselective biohydroxylation.Catalysis Science & Technology, 2022,12, 5703-5708.

（10）Jing Wang, Hezhen Wang, Chunyong Wei, Lei Zhang, Baodong Cui, Zhongqiang Wang, Yun Zhang, Nanwei Wan, Haji Akber Aisa and Yongzheng Chen, Combined photoredox/engineered P450 enzymatic direct dioxygen-functionalization of arylalkanes to chiral acyloins, Organic & Biomolecular Chemistry, 2022,20, 9085-9092.

（11）Jiajing Li, Wenjing Gu, Zhongqiang Wang, Xiaojian Zhou, Yongzheng Chen, Asymmetric Bio-Epoxidation of Unactivated Alkenes, ChemBioChem. 2023. DOI: 10.1002/cbic.202200719

（12）Hai Bo Cui ; Ting Ma; Ru Yue Zhang; Jing Shan; Zhongqiang Wang; Mei Bai; Yongzheng Chen; Biocatalytic Synthesis of Chiral Benzylic Alcohols via Enantioselective Hydroxylation by a Self-Sufficient Cytochrome P450 from Deinococcus gobiensis. DOI: 10.1055/a-2076-9792

（13）Yongzheng Chen*; Liu Song; Zhongqiang Wang; Biocatalytic Synthesis of Chiral 1,2,3,4-Tetrahydroquinolines, In Pharmaceutical Biocatalysis: Chemoenzymatic Synthesis of Active Pharmaceutical Ingredients, Peter Grunwald, Eds, Jenny Stanford Publishing: Singapore, 2019, Vol.5, 681-696

（14）Samuel A. Fraser#, Mantas Liutkus, Zhongqiang Wang, Chris J. Easton*, Incorporation of functionalized amino acids during cell-free protein expression. Amino Acids, 2015, 47(8): 1656-1656